Endocrine Abstracts

Objectives: Polycystic ovary syndrome (PCOS) and thyroid disorders have separately been linked to adverse pregnancy and neonatal outcomes. Even small variations in thyroid function within the normal range may influence fetal growth. Previous data have shown that metformin-treatment of pregnant women with PCOS reduced late miscarriages and preterm births, and resulted in less decrease of fT4 compared to placebo. Moreover, metformin exposure in utero altered the offspring anthro...

Background: Anti-Müllerian hormone (AMH) has a positive linear relationship to antral follicle count (AFC) in healthy women. However, studies of intra-follicular AMH-levels indicate a non-linear relation to AFC. It is speculated whether high AMH in polycystic ovary syndrome (PCOS) women is due to overactive follicles rather than directly reflect AFC.Study design: We used data from a previous case–control study, including 262 women with prior te...

Introduction: PCOS-related hormonal and metabolic alterations seem to persist later in life. The aim was to investigate age-related hormonal and metabolic parameters in PCOS and in healthy women in order to determine cut-off values predicting PCOS.Subjects and methods: PCOS women and 230 healthy controls were divided accordingly: 18–24, 25–29, 30–34, 35–39, 40–44, 45–49 and >50 years. A particular interest was to analyze...